2024

Ponomarova O, Starbard AN, Belfi A, Anderson AV, Sundaram MV, Walhout AJ. idh-1 neomorphic mutation confers sensitivity to vitamin B12 in Caenorhabditis elegans. Life Sci Alliance. 2024 Oct;7(10). doi: 10.26508/lsa.202402924. Print 2024 Oct. PubMed PMID: 39009411; PubMed Central PMCID: PMC11249921.

2023

Doshi MB, Lee N, Tseyang T, Ponomarova O, Goel HL, Spears M, Li R, Zhu LJ, Ashwood C, Simin K, Jang C, Mercurio AM, Walhout AJM, Spinelli JB, Kim D. Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells. Nature. 2023 Nov;623(7987):625-632. doi: 10.1038/s41586-023-06676-3. Epub 2023 Oct 25. PubMed PMID: 37880368; PubMed Central PMCID: PMC10709823.

Ponomarova O, Zhang H, Li X, Nanda S, Leland TB, Fox BW, Starbard AN, Giese GE, Schroeder FC, Yilmaz LS, Walhout AJM. A D-2-hydroxyglutarate dehydrogenase mutant reveals a critical role for ketone body metabolism in Caenorhabditis elegans development. PLoS Biol. 2023 Apr;21(4):e3002057. doi: 10.1371/journal.pbio.3002057. eCollection 2023 Apr. PubMed PMID: 37043428; PubMed Central PMCID: PMC10096224.

Sayin S, Rosener B, Li CG, Ho B, Ponomarova O, Ward DV, Walhout AJM, Mitchell A. Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy in co-cultured cancer cells. Elife. 2023 Feb 3;12. doi: 10.7554/eLife.83140. PubMed PMID: 36734518; PubMed Central PMCID: PMC9931390.

2022

Diot C, García-González AP, Vieira AF, Walker M, Honeywell M, Doyle H, Ponomarova O, Rivera Y, Na H, Zhang H, Lee M, Olsen CP, Walhout AJM. Bacterial diet modulates tamoxifen-induced death via host fatty acid metabolism. Nat Commun. 2022 Sep 23;13(1):5595. doi: 10.1038/s41467-022-33299-5. PubMed PMID: 36151093; PubMed Central PMCID: PMC9508336.

Ponomarova O. Teaming up to make kombucha. Elife. 2022 Aug 11;11. doi: 10.7554/eLife.81670. PubMed PMID: 35950918; PubMed Central PMCID: PMC9371600.

Fox BW, Ponomarova O, Lee YU, Zhang G, Giese GE, Walker M, Roberto NM, Na H, Rodrigues PR, Curtis BJ, Kolodziej AR, Crombie TA, Zdraljevic S, Yilmaz LS, Andersen EC, Schroeder FC, Walhout AJM. C. elegans as a model for inter-individual variation in metabolism. Nature. 2022 Jul;607(7919):571-577. doi: 10.1038/s41586-022-04951-3. Epub 2022 Jul 6. PubMed PMID: 35794472; PubMed Central PMCID: PMC9817093.

2021

Walker MD, Giese GE, Holdorf AD, Bhattacharya S, Diot C, García-González AP, Horowitz BB, Lee YU, Leland T, Li X, Mirza Z, Na H, Nanda S, Ponomarova O, Zhang H, Zhang J, Yilmaz LS, Walhout AJM. WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization. Genetics. 2021 Aug 26;219(1). doi: 10.1093/genetics/iyab089. PubMed PMID: 34117752; PubMed Central PMCID: PMC8864737.

2020

Giese GE, Walker MD, Ponomarova O, Zhang H, Li X, Minevich G, Walhout AJ. Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor. Elife. 2020 Oct 5;9. doi: 10.7554/eLife.60259. PubMed PMID: 33016879; PubMed Central PMCID: PMC7561351.

2019

Sahu AD, S Lee J, Wang Z, Zhang G, Iglesias-Bartolome R, Tian T, Wei Z, Miao B, Nair NU, Ponomarova O, Friedman AA, Amzallag A, Moll T, Kasumova G, Greninger P, Egan RK, Damon LJ, Frederick DT, Jerby-Arnon L, Wagner A, Cheng K, Park SG, Robinson W, Gardner K, Boland G, Hannenhalli S, Herlyn M, Benes C, Flaherty K, Luo J, Gutkind JS, Ruppin E. Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy. Mol Syst Biol. 2019 Mar 11;15(3):e8323. doi: 10.15252/msb.20188323. PubMed PMID: 30858180; PubMed Central PMCID: PMC6413886.

2018

Na H, Ponomarova O, Giese GE, Walhout AJM. C. elegans MRP-5 Exports Vitamin B12 from Mother to Offspring to Support Embryonic Development. Cell Rep. 2018 Mar 20;22(12):3126-3133. doi: 10.1016/j.celrep.2018.02.100. PubMed PMID: 29562169; PubMed Central PMCID: PMC5896776.

2017

Ponomarova O, Gabrielli N, Sévin DC, Mülleder M, Zirngibl K, Bulyha K, Andrejev S, Kafkia E, Typas A, Sauer U, Ralser M, Patil KR. Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow. Cell Syst. 2017 Oct 25;5(4):345-357.e6. doi: 10.1016/j.cels.2017.09.002. Epub 2017 Sep 27. PubMed PMID: 28964698; PubMed Central PMCID: PMC5660601.

2016

Jouhten P, Ponomarova O, Gonzalez R, Patil KR. Saccharomyces cerevisiae metabolism in ecological context. FEMS Yeast Res. 2016 Nov;16(7). doi: 10.1093/femsyr/fow080. Epub 2016 Sep 14. Review. PubMed PMID: 27634775; PubMed Central PMCID: PMC5050001.

2015

Ponomarova O, Patil KR. Metabolic interactions in microbial communities: untangling the Gordian knot. Curr Opin Microbiol. 2015 Oct;27:37-44. doi: 10.1016/j.mib.2015.06.014. Epub 2015 Jul 24. Review. PubMed PMID: 26207681.

Zelezniak A, Andrejev S, Ponomarova O, Mende DR, Bork P, Patil KR. Metabolic dependencies drive species co-occurrence in diverse microbial communities. Proc Natl Acad Sci U S A. 2015 May 19;112(20):6449-54. doi: 10.1073/pnas.1421834112. Epub 2015 May 4. PubMed PMID: 25941371; PubMed Central PMCID: PMC4443341.